SWITZERLAND—Nestlé Research in Switzerland and the National University of Singapore Sleep Center have published promising results on the efficacy of a unique bioactive blend in increasing natural sleepiness and sleep quality.

This research aimed at revealing a crucial role that sleep plays in people’s health and well-being, with both quantity and quality impacting overall wellness.

With people spending almost one-third of their lives sleeping, this clinical trial needed to determine the effect of a novel nutritional solution including a blend of bioactive substances on sleep.

Results from the study indicated that the combination of natural tryptophan, vitamin B, magnesium, zinc, melatonin-facilitating nutrients, and mulberry leaf extract reduced both measured and self-reported time to fall asleep by approximately 15%.

Additionally, the presence of the natural mulberry leaf extract, a traditional ingredient used in China, the bioactive blend reduced the postprandial blood sugar increase after the evening meal and glycemic variation during the night.

Speaking while presenting the findings, Eline van der Beek, Head of Nestlé’s Institute of Health Sciences, emphasized that the innovative use of digital technology and wearable devices to measure participants’ glucose levels and sleep quality, enabled reliable data collection on the nutritional solution’s effectiveness.

Leveraging these scientific findings, Nestlé’s R&D scientists developed a new milk powder containing the patented bioactive blend, targeting individuals aged 40-60 years. The product, Yiyang Wanning milk powder, has been launched in China.

Nestlé R+D Accelerator in Switzerland piloted easy-to-use fruit shots containing the proprietary blend, aimed at supporting sleep. The fruit shots were tested in Europe and South-East Asia.

On her part, Isabelle Bureau-Franz, Nestlé’s Head of R&D for the Nutrition category, highlighted that the company’s collaborative approach between scientific research and product development, enabling the translation of scientific discoveries into innovative sleep solutions across different formats.

In addition to these innovations, Nestlé introduced Nature’s Bounty Sleep3 Gummies in the U.S. last year.

Developed by experts at the R&D centre for Nestlé Health Sciences in Bridgewater, New Jersey, these gummies utilize proprietary technology for extended-release melatonin to aid relaxation, sleep onset, and sleep maintenance. 

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