The new NBI+TXI mode improves on the existing NBI mode by enhancing brightness and contrast, allowing clearer views of darker image areas.

JAPAN— Olympus Corporation, a global MedTech company dedicated to improving health and safety, has introduced the new NBI+TXI™ observation mode.
This mode combines Narrow Band Imaging (NBI™) and Texture and Color Enhancement Imaging (TXI™) into a single view, enhancing the diagnostic capabilities of the EVIS X1™ endoscopy system.
Sales of the EVIS X1 featuring the NBI+TXI mode will begin in Japan in November 2025, with other regions following after regulatory approvals.
Since its release in April 2020, the EVIS X1 endoscopy system has offered advanced imaging options, including TXI, NBI, and Red Dichromatic Imaging (RDI™).
These innovations help healthcare professionals observe and treat gastrointestinal and respiratory diseases, including cancer, with greater precision.
The new NBI+TXI mode improves on the existing NBI mode by enhancing brightness and contrast, allowing clearer views of darker image areas.
This technology enhances visualisation of blood vessels and mucosal patterns, enabling better detection and more accurate diagnosis of lesions, including cancerous ones.
Data from Japan’s Ministry of Health, Labour and Welfare in 2021 highlight the importance of such innovations.
Colorectal cancer is the most common cancer with 154,585 cases, followed by lung cancer with 124,531 cases, and stomach cancer with 112,881 cases.
These cancers are also among the leading causes of cancer deaths in Japan, with lung cancer causing 75,762 deaths, colorectal cancer 53,131, and stomach cancer 38,771.
NBI first appeared worldwide in 2006 and revolutionized endoscopic imaging by revealing previously hidden features.
The CV-1500 endoscopy system incorporates the latest version of NBI, offering improved brightness over the original.
TXI mode, introduced alongside the CV-1500, further enhances lesion visibility by improving texture, brightness, and color contrast under conventional light.
By combining NBI and TXI technologies, the new NBI+TXI mode on the CV-1500 enhances contrast for more precise endoscopic exams and treatments.
TXI mode highlights inflammation, flat or depressed lesions, and tiny early lesions by clarifying subtle tissue differences, potentially leading to higher detection rates and better diagnosis.
NBI enhances contrast between blood vessels and surrounding tissues using specific blue and green wavelengths to support early lesion detection and improve diagnostic confidence.
Kurt Heine, Senior Vice President and General Manager for Gastroenterology at Olympus, emphasized that early detection is crucial for better patient care and outcomes.
He expressed enthusiasm about expanding the EVIS X1 system’s capabilities with the new combined imaging mode to raise the standard of care.
Physicians attending the JDDW conference from October 30 to November 1, 2025, at the Kobe Convention Center will have the chance to experience the NBI+TXI imaging mode firsthand.
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