Ennogen, which focuses on European markets, will acquire the rights and intellectual property, while Aspen will retain a manufacturing and supply role under long-term agreements.
The nearly R20 million (US$1.20 million) development will increase the facility’s capacity from 15 bedrooms accommodating 30 mothers to 36 bedrooms serving 72 mothers.
The Medicines and Healthcare products Regulatory Agency (MHRA) approved the expanded indication, lowering the minimum eligible age from 12 to five years for both conditions.
Lonza also plans to introduce 500-litre single-use manufacturing capacity across its existing mid-scale bioconjugation facilities from 2027.
AstraZeneca plans to reinvest most of the savings in research and development, although the programme is expected to incur up to US$2 billion in one-time restructuring costs over three years.
The clinical-stage biotechnology company will also use the proceeds to expand its research pipeline across autoimmune diseases, immunology, neurological disorders and oncology.
The new sterile manufacturing plant will complement Bracco’s existing production operations in Europe, Asia and Canada, expanding its global manufacturing network.
The facility operates in accordance with requirements established by the US Food and Drug Administration (FDA) and the Drug Enforcement Administration (DEA).
Operated by OMRON HEALTHCARE MANUFACTURING INDIA Pvt. Ltd., the approximately 24,000-square-metre factory is located at ORIGINS by Mahindra and has five production lines serving the Indian market.
The proposal, developed under the Global Fund’s Grant Cycle 8 (GC8), seeks US$339.6 million for HIV, US$16.1 million for TB and US$82.2 million for malaria.