Sanofi will pay Regeneron US$1 billion upfront, with development, regulatory, and commercial milestones potentially adding another US$ 7 billion.
The deal builds on a relationship between the companies that began in 2014, including previous transfers of mature medicines from Sanofi to Cheplapharm.
The latest decision marks another setback for amlitelimab, which Sanofi had previously positioned as a potential successor to Dupixent, its best-selling immunology asset.
The approval expands the use of the therapy to delay the onset of Stage 3 Type 1 diabetes in children as young as one year old.
The proposed centre will operate within Abu Dhabi’s Health, Endurance, Longevity, and Medicine (HELM) Cluster, a strategic life sciences platform that integrates research, healthcare delivery, investment, commercialization, and biomanufacturing.
The project is backed by a conditional grant of up to C$5 million (US$3.6 million) from the Ontario government through the Invest Ontario Fund.
Less than 10% of participants in the Nuvaxovid group experienced severe side effects that interfered with daily activities compared with 20% in the mNexspike group.
The Maisons-Alfort plant, which previously operated under Sanofi’s ownership, specializes in fill-finish manufacturing at commercial scale.
Rather than consolidating operations through plant closures, EMS intends to retain Medley’s existing facilities and invest in future expansion.
The agreement includes a USD135 million upfront payment to Sino Biopharmaceutical for worldwide rights, with up to USD1.39 billion in potential milestone payments based on development, regulatory approvals, and sales.