TLB 33 is a human immunoglobulin G1 monoclonal antibody designed to bind to and neutralise interleukin 33, an immune signalling protein.
Under the agreement, LEO will pay up to US$435 million in upfront and near-term milestone payments for global rights to dersimelagon.
The transaction, announced on July 3, includes Tanabe Pharma Factory’s production facilities in Onoda and Yoshitomi.