Siemens Healthineers introduces AI-powered coronary analysis software at RSNA 2025

USA—Siemens Healthineers has introduced Syngo.CT Coronary Cockpit at RSNA 2025, a new software solution within the Syngo.via platform designed to improve the management of coronary artery disease (CAD).

The software works with both dual-source and photon-counting CT scanners to provide advanced diagnostic capabilities.

CAD remains the leading cause of death worldwide and contributes significantly to disability across populations.

This reality drives growing demand for diagnostic tools that are efficient yet minimally invasive.

Syngo.CT Coronary Cockpit addresses these needs through automated plaque analysis, making critical information embedded in cardiac CT images readily accessible to clinicians.

The software supports clinical decision-making and helps physicians plan interventions more effectively.

Dr. Balint Szilveszter from the Heart and Vascular Centre at Semmelweis University in Budapest, Hungary, highlighted the clinical value of this innovation.

He noted that CT images contain vast amounts of information that often remain inaccessible.

Syngo.CT Coronary Cockpit provides an automated, rapid approach to unlock this data and integrate it into daily clinical practice.

Physicians can use this information to optimize medical therapy or plan percutaneous coronary intervention (PCI) procedures before patients enter the catheterization laboratory.

Many patients with suspected or known CAD traditionally undergo diagnostic procedures in the cath lab, even though these procedures could often be avoided.

Recent advances in cardiac CT technology, particularly with dual-source and photon-counting CT scanners, have established non-invasive coronary CT angiography (CCTA) as a primary diagnostic tool.

Research demonstrates that using CCTA with Siemens Healthineers’ Naeotom Alpha CT scanner can reduce referrals for diagnostic angiography by more than half while lowering costs and shortening hospital stays.

Syngo.CT Coronary Cockpit enhances diagnostic confidence by characterizing both the volume and morphology of coronary plaque through AI-based segmentation, labeling, and visualization.

The software analyzes plaque composition, size, and distribution, enabling clinicians to assess risk more accurately and select appropriate treatments, whether medical management or intervention.

The integration of this software with Siemens Healthineers’ dual-source and photon-counting CT scanners delivers high native temporal resolution, supporting clinical accuracy and operational efficiency throughout the CAD care pathway.

When detailed anatomical and morphological information becomes available before an interventional procedure, cath lab efficiency improves, and resource utilization is optimized.

Clinicians gain comprehensive insights into coronary anatomy and pathology, supporting more precise plaque assessment and informing critical decisions about lesion preparation, stent length, and landing-zone selection.

Philipp Fischer, head of Computed Tomography at Siemens Healthineers, emphasized that Syngo.CT Coronary Cockpit combines the company’s expertise in CT imaging and interventional therapy to help people with coronary artery disease live longer, healthier lives.

This integrated approach represents an important step toward CT-guided PCI and advances the goal of delivering personalized, minimally invasive care to patients.